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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNB1
All Species:
51.21
Human Site:
Y258
Identified Species:
93.89
UniProt:
P14635
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14635
NP_114172.1
433
48337
Y258
A
M
F
I
A
S
K
Y
E
E
M
Y
P
P
E
Chimpanzee
Pan troglodytes
XP_517728
536
59103
Y361
A
M
F
I
A
S
K
Y
E
E
M
Y
P
P
E
Rhesus Macaque
Macaca mulatta
XP_001091533
433
48375
Y258
A
M
F
I
A
S
K
Y
E
E
M
Y
P
P
E
Dog
Lupus familis
XP_850398
425
47378
Y250
A
M
F
I
A
S
K
Y
E
E
M
Y
P
P
E
Cat
Felis silvestris
Mouse
Mus musculus
P24860
430
48033
Y255
A
M
F
I
A
S
K
Y
E
E
M
Y
P
P
E
Rat
Rattus norvegicus
P30277
423
47373
Y248
A
M
F
I
A
S
K
Y
E
E
M
Y
P
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507609
428
47366
Y253
A
M
F
I
A
S
K
Y
E
E
M
Y
P
P
E
Chicken
Gallus gallus
P29332
399
44633
Y226
A
L
L
L
A
S
K
Y
E
E
M
Y
S
P
D
Frog
Xenopus laevis
P13350
397
44655
Y224
A
M
F
L
A
A
K
Y
E
E
M
Y
P
P
E
Zebra Danio
Brachydanio rerio
NP_571588
398
44818
Y225
A
M
F
I
A
S
K
Y
E
E
M
Y
P
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20439
530
59237
Y347
A
L
F
I
A
T
K
Y
E
E
L
F
P
P
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39071
444
50417
Y270
C
M
L
I
A
S
K
Y
E
E
I
S
A
P
R
Baker's Yeast
Sacchar. cerevisiae
P24869
491
56228
Y317
C
L
F
I
A
S
K
Y
E
E
V
Y
S
P
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.5
98.6
91.2
N.A.
86.3
84.7
N.A.
75.7
50.5
66.2
61.8
N.A.
34.3
N.A.
N.A.
N.A.
Protein Similarity:
100
80.5
99.3
94
N.A.
91.9
90.5
N.A.
84.5
66.9
78.2
75.7
N.A.
49.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
66.6
86.6
100
N.A.
66.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
86.6
100
100
N.A.
93.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
30.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.1
48.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
85
0
0
0
100
8
0
0
0
0
0
0
8
0
8
% A
% Cys:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
100
100
0
0
0
0
70
% E
% Phe:
0
0
85
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
85
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% K
% Leu:
0
24
16
16
0
0
0
0
0
0
8
0
0
0
0
% L
% Met:
0
77
0
0
0
0
0
0
0
0
77
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
77
100
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
85
0
0
0
0
0
8
16
0
8
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
85
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _